The management of infection with Mycobacterium tuberculosis in young children post-2015: an opportunity to close the policy-practice gap.
Identifieur interne : 000190 ( Main/Exploration ); précédent : 000189; suivant : 000191The management of infection with Mycobacterium tuberculosis in young children post-2015: an opportunity to close the policy-practice gap.
Auteurs : Stephen M. Graham [Australie]Source :
- Expert review of respiratory medicine [ 1747-6356 ] ; 2017.
Descripteurs français
- KwdFr :
- MESH :
- traitement médicamenteux : Tuberculose.
- usage thérapeutique : Antituberculeux.
- Différences de pratiques professionnelles, Enfant, Humains, Mycobacterium tuberculosis, Systèmes automatisés lit malade, Tuberculose.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Antitubercular Agents.
- drug therapy : Tuberculosis.
- prevention & control : Tuberculosis.
- Child, Humans, Mycobacterium tuberculosis, Point-of-Care Systems, Professional Practice Gaps.
Abstract
The treatment of infection with Mycobacterium tuberculosis in young children is supported by universal policy based on strong rationale and evidence of effectiveness, but has rarely been implemented in tuberculosis endemic countries. Areas covered: This review highlights a number of important recent developments that provide an unprecedented opportunity to close the policy-practice gap, as well as ongoing needs to facilitate implementation under programmatic conditions and scale-up. Expert commentary: The WHO's End TB Strategy and Stop TB Partnership's Plan to End TB provide ambitious targets for prevention at a time when National Tuberculosis Programs in tuberculosis endemic countries are increasing attention to the challenges of management and prevention of tuberculosis disease in children. This opportunity is greatly enhanced by recent evidence of the effectiveness of shorter, simpler and safer regimens to treat tuberculosis infection. The scale of the challenge for implementation will require a decentralized, integrated, community-based approach. An accurate and low-cost point-of-care test for tuberculous infection would be a major advance to support such implementation. Specific guidance for the treatment of infection in young child contacts of multidrug-resistant tuberculosis cases is a major current need while awaiting further evidence.
DOI: 10.1080/17476348.2016.1267572
PubMed: 27910720
Affiliations:
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Le document en format XML
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Graham</name><affiliation wicri:level="1"><nlm:affiliation>a Centre for International Child Health, University of Melbourne Department of Paediatrics and Murdoch Childrens Research Institute , Royal Children's Hospital , Melbourne , Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>a Centre for International Child Health, University of Melbourne Department of Paediatrics and Murdoch Childrens Research Institute , Royal Children's Hospital , Melbourne </wicri:regionArea><wicri:noRegion>Melbourne </wicri:noRegion></affiliation></author></analytic><series><title level="j">Expert review of respiratory medicine</title><idno type="eISSN">1747-6356</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antitubercular Agents (therapeutic use)</term><term>Child</term><term>Humans</term><term>Mycobacterium tuberculosis</term><term>Point-of-Care Systems</term><term>Professional Practice Gaps</term><term>Tuberculosis (drug therapy)</term><term>Tuberculosis (prevention & control)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Antituberculeux (usage thérapeutique)</term><term>Différences de pratiques professionnelles</term><term>Enfant</term><term>Humains</term><term>Mycobacterium tuberculosis</term><term>Systèmes automatisés lit malade</term><term>Tuberculose ()</term><term>Tuberculose (traitement médicamenteux)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antitubercular Agents</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Tuberculosis</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Tuberculosis</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Tuberculose</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antituberculeux</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Child</term><term>Humans</term><term>Mycobacterium tuberculosis</term><term>Point-of-Care Systems</term><term>Professional Practice Gaps</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Différences de pratiques professionnelles</term><term>Enfant</term><term>Humains</term><term>Mycobacterium tuberculosis</term><term>Systèmes automatisés lit malade</term><term>Tuberculose</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The treatment of infection with Mycobacterium tuberculosis in young children is supported by universal policy based on strong rationale and evidence of effectiveness, but has rarely been implemented in tuberculosis endemic countries. Areas covered: This review highlights a number of important recent developments that provide an unprecedented opportunity to close the policy-practice gap, as well as ongoing needs to facilitate implementation under programmatic conditions and scale-up. Expert commentary: The WHO's End TB Strategy and Stop TB Partnership's Plan to End TB provide ambitious targets for prevention at a time when National Tuberculosis Programs in tuberculosis endemic countries are increasing attention to the challenges of management and prevention of tuberculosis disease in children. This opportunity is greatly enhanced by recent evidence of the effectiveness of shorter, simpler and safer regimens to treat tuberculosis infection. The scale of the challenge for implementation will require a decentralized, integrated, community-based approach. An accurate and low-cost point-of-care test for tuberculous infection would be a major advance to support such implementation. Specific guidance for the treatment of infection in young child contacts of multidrug-resistant tuberculosis cases is a major current need while awaiting further evidence.</div></front></TEI><affiliations><list><country><li>Australie</li></country></list><tree><country name="Australie"><noRegion><name sortKey="Graham, Stephen M" sort="Graham, Stephen M" uniqKey="Graham S" first="Stephen M" last="Graham">Stephen M. Graham</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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